Oxygen (O2) transport and BloodVitals experience hemostasis are central to human adaptation to stress/injury and to disease pathobiology. The interdisciplinary Center for Blood Oxygen Transport & Hemostasis (CBOTH) addresses basic, difficult questions associated to blood O2 transport and hemostasis from a systems perspective, with consideration to human biology, physiology and BloodVitals device therapeutics. Innovative examine of O2 transport, hemostasis and key interacting biologic methods crosses conventional disciplines